Organic Acids Articles and Webinars
Webinars
Articles
Kurt Woeller, DO
The Organic Acids Test (OAT) is profile essential in functional and integrative health assessment for most anyone dealing with a chronic health problem. The OAT measures various compounds that provide insight into candida overgrowth, bacterial infections, oxalate, mitochondrial dysfunction, neurotransmitter imbalances and much more. A one-day intensive seminar on the implementation of the OAT, and other more advanced lectures on OAT interpretation and clinical application are available. However, before taking part in these clinical trainings, unless you already have experience in OAT use, there are fundamental concepts that are critical to understand. This webinar by Kurt N. Woeller, D.O. is focused on the basics of the Organic Acids Test. You can consider this lecture to be an introduction or a 101-level lecture about the OAT.
Kurt Woeller, DO
The Organic Acids Test (OAT) is profile essential in functional and integrative health assessment for most anyone dealing with a chronic health problem. The OAT measures various compounds that provide insight into candida overgrowth, bacterial infections, oxalate, mitochondrial dysfunction, neurotransmitter imbalances and much more. A one-day intensive seminar on the implementation of the OAT, and other more advanced lectures on OAT interpretation and clinical application are available. However, before taking part in these clinical trainings, unless you already have experience in OAT use, there are fundamental concepts that are critical to understand. This webinar by Kurt N. Woeller, D.O. is focused on the basics of the Organic Acids Test. You can consider this lecture to be an introduction or a 101-level lecture about the OAT.
Kurt Woeller, DO
Various molds like Aspergillus can produce toxic chemical compounds that damage cellular function. The mold itself can trigger immune reactions which drive inflammation, but mycotoxins (aka mold toxins) have their own chemical properties when targeted against the kidneys and liver which can lead to detoxification interference. This lecture by Kurt N. Woeller, D.O. will discuss some of the mechanisms involved that underlie liver and kidney problems linked to certain mold toxins.
Kurt Woeller, DO
Glyphosate, used as an organophosphate herbicide on genetically modified agricultural plants, has many adverse biochemical manipulating properties. This webinar will discuss the link between glyphosate use, oxalic acid, and associated problems at the mitochondria level.
Kurt Woeller, DO
Fungal infections of various types can initiate immune dysfunction leading to systemic infection and serious disease. The overuse of antibiotics and subsequent microbiome disruption, along with other factors, e.g., nutrient imbalances, mucosal surface damage, can increase the potential for autoimmunity and related diseases. Various immune cells and their cytokines are intimately involved in regulating mucosal reactivity to opportunistic fungus. It is the dysregulation of these factors which create the potential for fungal related autoimmunity. This webinar will explore these details and more.
Kurt Woeller, DO
Magnesium is an important mineral for many biochemical reactions in the human body. Much attention is given to its influence within the digestive system or cardiovascular activity. This lecture will explore these and other aspects of the various biochemical influences of this important mineral.
Kurt Woeller, DO
Digestive bacterial markers on the Organic Acids Test (OAT) do not typically get as much attention compared to the clostridia toxins such as 4-Cresol and HPHPA. However, there are some important clinical considerations to pay attention to when markers in the Bacterial Metabolite section of the OAT show up elevated.
Kurt Woeller, DO
Vitamin D is an essential nutrient well known for its role in immune function, bone metabolism, and reduction in cardiovascular diseases. However, there are other less-known effects of vitamin D that this lecture will explore, including its influence on cellular metabolism linked to mitochondrial activity and neurochemical regulation within the nervous system.
Kurt Woeller, DO
Various mycotoxins can have significant adverse effects with regards to cellular function. Through DNA and RNA disruption and/or induction of oxidative stress mycotoxins can lead to various diseases, including cancer. A major target of intracellular mycotoxins are the mitochondria. This lecture by Dr. Kurt Woeller will discuss some of the cytotoxic effects of mycotoxins on mitochondrial function.
Kurt Woeller, DO
Acrolein is a common chemical to appear on the non-metal chemical profile, the GPL-TOX. Since its addition to this lab test, approximately 80% of people tested have levels of acrolein near or above the 95th percentile. Commonly added to irrigation canals to control algae overgrowth, it is also used in the gas and oil industry as a biocide, and can occur from cigarette smoke. Acrolein is also produced by digestive bacteria, including clostridium. This video discusses exposure sources to acrolein, its toxicity, related health problems, and information about what to look for on the Organic Acids Test when acrolein levels are elevated on the GPL-TOX Profile.
Kurt Woeller, DO
The Organic Acids Test (OAT) contains multiple markers which may be influenced by environmental and mold toxins. Often the combination of the OAT, MycoTOX Profile (mold toxins), and GPL-TOX Profile (environmental chemical toxins) can be used to help identify exposure sources and biochemical imbalances in individuals with chronic health conditions. This presentation by Kurt N. Woeller, DO will help connect some of the more common findings seen in practice when evaluating these three tests.
Kurt Woeller, DO
Autism and other special needs individuals often have biochemical and nutritional imbalances that contribute to language, socialization, and behavioral problems. In some situations, these issues are exacerbated by fungal toxins linked to chronic candidiasis and mold-produced compounds. For example, chemical aldehydes from fungus are known to be highly reactive compounds that need to be converted to less toxic forms via converting enzymes and phase detoxification within the liver. These aldehydes and other compounds can have detrimental effects within the body. The use of various nutrients such as N-acetylcysteine (NAC), etc. are often essential in supporting the body against fungal toxins. This lecture designed for health professionals, as well as parents and caregivers will discuss new information related to certain fungal toxins and strategies for treatment.
Kurt Woeller, DO, Dane Johnson, CHN, and Jon Sheflet discuss how the OAT and MycoTOX Profile play a role in the recovery of patients with Crohns/Colitis.
Jasmyne Brown, ND
This webinar will discuss some common toxins assessed on the GPL-TOX Profile. We will discuss the effects of exposure and where to find these common toxins. Briefly, we will take a look into options for testing the environment to identify potential exposure in your everyday life.
Kurt Woeller, DO
Various candida organisms can be normal inhabitants of the digestive system and part of the microbiome in low levels. However, candida has the potential to overpopulate the bowel leading to various symptoms of bloating, gas, constipation, etc. Candida can also become invasive within the digestive system leading to leaky gut and increasing mucosal immune activity and systemic reactivity. This will be a special roundtable discussion allowing practitioners to submit specific case studies and will focus more on direct Q&A on specific case studies.
In this live webinar, hosted by Autism Research Coalition, William Shaw, PhD & Sidney Baker, MD discussed their latest publication "Case Study: Rapid Complete Recovery From An Autism Spectrum Disorder After Treatment of Aspergillus With The Antifungal Drugs Itraconazole And Sporanox" (2020).
As noted in the publication, "Escalation of the dose of itraconazole resulted in a complete loss of all symptoms of Autism over the course of 3 months. This rapid complete reversal of Autism is consistent with several articles proposing mold in general and Aspergillus specifically as a potential major cause of Autism."
Dr. Sidney Baker was the co-founder of Defeat Autism Now!, a national organization devoted to dialog among parents, practitioners and scientists regarding biomedical treatment options and the environmental origins of the current Autism epidemic. He received his undergraduate, medical, and medical postgraduate training from Yale University where he served as Chief Resident in Pediatrics on the full-time medical faculty. He is the author of multiple books and publications and was the 1999 recipient of the Linus Pauling Award of the Institute for Functional Medicine for his contributions to the development of Functional Medicine, to name a few achievements.
Dr. William Shaw is board certified in the fields of clinical chemistry and toxicology by the American Board of Clinical Chemistry and the founder of The Great Plains Laboratory. Dr. Shaw worked for the Centers for Disease Control and Prevention (CDC), Children's Mercy Hospital, University of Missouri at Kansas City School of Medicine, and Smith Kline Laboratories. He is the author of Biological Treatments for Autism and PDD, originally published in 1998 and Autism: Beyond the Basics, published in 2009. Dr. Shaw is the stepfather of a child with Autism and has helped thousands of patients and medical practitioners to successfully improve the lives of people with autism, ADHD, Alzheimer's disease, and other serious conditions.
In a live webinar, presented by the Autism Research Coalition, William Shaw, PhD reviewed his research that identified several compounds in the urine of children with Autism Spectrum Disorder (ASD) using gas chromatography mass spectrometry. Many of these compounds (elevated in ASD) were associated with the presence of mold and yeast in the gastrointestinal tract. The children with ASD had significantly higher values compared to healthy controls in these compounds.
Antifungal therapy as a treatment for ASD became much more common throughout the world because of this study and the concerted efforts by Dr. Sidney Baker to use what he called the “antifungal parade” to treat ASD, although it was not completely clear if the benefits of antifungal treatments were due to the control of yeast (Candida), mold, or both. Recently Dr. Baker treated a young boy with significant ASD using the drugs Itraconazole and Sporanox, drugs that are very useful for the control of many molds. As a result of the treatment, the child had a complete and very rapid recovery from ASD. Testing at The Great Plains Laboratory found that the child’s rapid recovery correlated with a drastic drop in metabolites associated with the mold Aspergillus.
Elevated pyroglutamic can appear on the Organic Acids Test (OAT) as an indicator of glutathione deficiency. Glutathione plays an important role in cellular protection as an antioxidant, as well as detoxification. This information, taken in part from Dr. Woeller’s Advanced OAT Mastery Course, will explain various clinical considerations of pyroglutamic biochemistry.
There are various laboratory tests useful in functional medicine. The Organic Acids Test (OAT) is one such profile which reveals a lot of important information that every integrative and functional medicine practitioner should learn how to interpret. This lecture will provide information useful for a new practitioner to the OAT and those more experienced in applying OAT information in clinical practice.
BHRT can be an effective method for replacing diminished sex hormones such as estrogen and testosterone. This lecture by Dr. Tracy Tranchitella will discuss modes of delivery (e.g. oral, transdermal), best absorption, follow-up testing and more.
Dysautonomia, associated with autonomic nervous system dysfunction, can manifest in various ways, including chronic fatigue, cognitive problems, cardiovascular dysfunction, e.g. low blood pressure, elevated heart rate, and mental health disorders. Lack of Thiamine (Vitamin B1), as one possibility of dysautonomia, can compromise mitochondrial function leading to imbalanced activity within the autonomic nervous system (ANS). There are other considerations too such as Dopamine Beta-Hydroxylase deficiency. This lecture will focus on certain aspects of dysautonomia.
Various candida organisms can be a normal inhabitant of the digestive system and part of our microbiome in low levels. However, candida has the potential to overpopulate the bowel leading to various symptoms of bloating, gas, constipation, etc. Candida can also become invasive within the digestive system leading to leaky gut increase immune activity and systemic reactivity. This lecture will highlight unique aspects of candidiasis, including certain pathogenicity mechanisms, laboratory tests, and treatment interventions.
The Organic Acids Test (OAT) is an important laboratory analysis for metabolic imbalances. This lecture is an overview of how to review an OAT and clinical considerations for common OAT markers. This lecture will prepare your for attending a GPL Academy OAT workshop and Dr. Kurt Woeller’s Essential OAT Mastery Course through his Integrative Medicine Academy.
Mitochondria are the energy factors of our cells. There are various things that can lead to problems in the mitochondria. This lecture will explore mitochondrial dysfunction from a functional medicine perspective.
We live in a world where we can extend our daytime activities well into the night but what has this done to our patterns of sleep, hormone production and overall well-being? The circadian rhythm is the 24-hour cycle of light and dark that we experience every day. Our response to light during the day and darkness at night sets the timing of key biological events, hormone production, detoxification and mechanisms for rest, recovery and repair.
This webinar will discuss the importance of adherence to patterns of sleep, food consumption and activity that support human physiology and can result in better hormone balance, stress tolerance, weight management and more.
This webinar aims to explain the importance of mycotoxin testing in the body and mold testing in the home. There will be an overview of the molds and mycotoxins tested in the MycoTOX Profile, as well as how the OAT can help practitioners understand the extent of a patient’s mold exposure. The webinar will also include an overview of common DIY mold testing services for the home, to help practitioners and patients alike determine where to begin their search for mold in their environment.
The OAT is a fundamental laboratory assessment for the detection of toxins and various biochemical imbalances. Dr. Kurt Woeller has lectured extensively on the use of the OAT in clinical practice. This lecture by Dr. Woeller will explore some deeper concepts of the OAT in preparation for the July 2020 release of his Advanced OAT Mastery Course through Integrative Medicine Academy.
Kurt Woeller, DO
Glyphosate, used as an organophosphate herbicide on genetically modified agricultural plants, has many adverse biochemical manipulating properties. This webinar will discuss the link between glyphosate use, oxalic acid, and associated problems at the mitochondria level.