Kurt Woeller, DO
Various molds like Aspergillus can produce toxic chemical compounds that damage cellular function. The mold itself can trigger immune reactions which drive inflammation, but mycotoxins (aka mold toxins) have their own chemical properties when targeted against the kidneys and liver which can lead to detoxification interference. This lecture by Kurt N. Woeller, D.O. will discuss some of the mechanisms involved that underlie liver and kidney problems linked to certain mold toxins.
Kurt Woeller, DO
Mycotoxins are toxic compounds produced by many different types of molds. A certain group of mycotoxins called trichothecenes are a large group of chemically related compounds produced by such molds as Fusarium and Stachybotrys. Trichothecenes have some unique toxicity effects, including on cellular production of proteins, DNA synthesis, and more. This lecture will explore various mycotoxins within the trichothecene family and some of their related cytotoxicities.
Kurt Woeller, DO
Vitamin D is an essential nutrient well known for its role in immune function, bone metabolism, and reduction in cardiovascular diseases. However, there are other less-known effects of vitamin D that this lecture will explore, including its influence on cellular metabolism linked to mitochondrial activity and neurochemical regulation within the nervous system.
Kurt Woeller, DO
The GPL-TOX Profile, aka, Non-Metal Chemical Profile is a useful assessment for environmental chemical exposures. Many chemicals are toxic to various cellular components, including the mitochondria. A marker on the GPL-TOX Profile called Tiglyglycine is often elevated in the presence of toxic chemicals. This lecture from Dr. Woeller will discuss what is the significance for a high Tiglyglycine and some reasons for its elevation.
Kurt Woeller, DO
Acrolein is a common chemical to appear on the non-metal chemical profile, the GPL-TOX. Since its addition to this lab test, approximately 80% of people tested have levels of acrolein near or above the 95th percentile. Commonly added to irrigation canals to control algae overgrowth, it is also used in the gas and oil industry as a biocide, and can occur from cigarette smoke. Acrolein is also produced by digestive bacteria, including clostridium. This video discusses exposure sources to acrolein, its toxicity, related health problems, and information about what to look for on the Organic Acids Test when acrolein levels are elevated on the GPL-TOX Profile.
Kurt Woeller, DO
The Organic Acids Test (OAT) contains multiple markers which may be influenced by environmental and mold toxins. Often the combination of the OAT, MycoTOX Profile (mold toxins), and GPL-TOX Profile (environmental chemical toxins) can be used to help identify exposure sources and biochemical imbalances in individuals with chronic health conditions. This presentation by Kurt N. Woeller, DO will help connect some of the more common findings seen in practice when evaluating these three tests.