Lab Testing

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The Role of Nicotinamide Riboside in Supporting Aging & Health

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Kurt N Woeller, DO

Nicotinamide, along with niacin (vitamin B3), linked nicotinamide adenine dinucleotide (NAD) production, are key components of the quinolinic acid-kynurenic pathway. Various supplemental forms of these nutrients exist that can be taken to support important cellular chemistry for energy production, etc. A form of nicotinamide called nicotinamide riboside (NR) is recognized as an important form of nicotinamide with usefulness for various conditions, including cardiovascular, neurodegenerative, and metabolic disorders. This lecture by Kurt N. Woeller, D.O. of Integrative Medicine Academy will explain the biochemistry of the quinolinic-kynurenic pathway in support of NAD, and the usefulness of niacinamide in the form of NR.

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The Organic Acids Test With A Focus On The Bacterial Metabolite Section

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Kurt Woeller, DO

Digestive bacterial markers on the Organic Acids Test (OAT) do not typically get as much attention compared to the clostridia toxins such as 4-Cresol and HPHPA. However, there are some important clinical considerations to pay attention to when markers in the Bacterial Metabolite section of the OAT show up elevated.

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Mycotoxin Induced Mitochondrial Dysfunction And Cytotoxicity

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Kurt Woeller, DO

Various mycotoxins can have significant adverse effects with regards to cellular function. Through DNA and RNA disruption and/or induction of oxidative stress mycotoxins can lead to various diseases, including cancer. A major target of intracellular mycotoxins are the mitochondria. This lecture by Dr. Kurt Woeller will discuss some of the cytotoxic effects of mycotoxins on mitochondrial function.

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Tiglyglycine Elevation And The GPL-TOX Profile

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Kurt Woeller, DO

The GPL-TOX Profile, aka, Non-Metal Chemical Profile is a useful assessment for environmental chemical exposures. Many chemicals are toxic to various cellular components, including the mitochondria. A marker on the GPL-TOX Profile called Tiglyglycine is often elevated in the presence of toxic chemicals. This lecture from Dr. Woeller will discuss what is the significance for a high Tiglyglycine and some reasons for its elevation.

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Acrolein Exposure, Toxicity, and Associated Health Problems

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Kurt Woeller, DO

Acrolein is a common chemical to appear on the non-metal chemical profile, the GPL-TOX. Since its addition to this lab test, approximately 80% of people tested have levels of acrolein near or above the 95th percentile. Commonly added to irrigation canals to control algae overgrowth, it is also used in the gas and oil industry as a biocide, and can occur from cigarette smoke. Acrolein is also produced by digestive bacteria, including clostridium. This video discusses exposure sources to acrolein, its toxicity, related health problems, and information about what to look for on the Organic Acids Test when acrolein levels are elevated on the GPL-TOX Profile.

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Connecting Specific Markers Amongst The Organic Acids Test (OAT), MycoTOX, and The Non-Metal Chemical (GPL-TOX) Profiles

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Kurt Woeller, DO

The Organic Acids Test (OAT) contains multiple markers which may be influenced by environmental and mold toxins. Often the combination of the OAT, MycoTOX Profile (mold toxins), and GPL-TOX Profile (environmental chemical toxins) can be used to help identify exposure sources and biochemical imbalances in individuals with chronic health conditions. This presentation by Kurt N. Woeller, DO will help connect some of the more common findings seen in practice when evaluating these three tests.

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Essential Integrative Medicine Lab Tests That Should Be Done for Anyone with Autism

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