GPL-TOX Resources

The Organic Acids Test With A Focus On The Bacterial Metabolite Section

Kurt Woeller, DO

Digestive bacterial markers on the Organic Acids Test (OAT) do not typically get as much attention compared to the clostridia toxins such as 4-Cresol and HPHPA. However, there are some important clinical considerations to pay attention to when markers in the Bacterial Metabolite section of the OAT show up elevated.

Tiglyglycine Elevation And The GPL-TOX Profile

Kurt Woeller, DO

The GPL-TOX Profile, aka, Non-Metal Chemical Profile is a useful assessment for environmental chemical exposures. Many chemicals are toxic to various cellular components, including the mitochondria. A marker on the GPL-TOX Profile called Tiglyglycine is often elevated in the presence of toxic chemicals. This lecture from Dr. Woeller will discuss what is the significance for a high Tiglyglycine and some reasons for its elevation.

Acrolein Exposure, Toxicity, and Associated Health Problems

Kurt Woeller, DO

Acrolein is a common chemical to appear on the non-metal chemical profile, the GPL-TOX. Since its addition to this lab test, approximately 80% of people tested have levels of acrolein near or above the 95th percentile. Commonly added to irrigation canals to control algae overgrowth, it is also used in the gas and oil industry as a biocide, and can occur from cigarette smoke. Acrolein is also produced by digestive bacteria, including clostridium. This video discusses exposure sources to acrolein, its toxicity, related health problems, and information about what to look for on the Organic Acids Test when acrolein levels are elevated on the GPL-TOX Profile.

Connecting Specific Markers Amongst The Organic Acids Test (OAT), MycoTOX, and The Non-Metal Chemical (GPL-TOX) Profiles

Kurt Woeller, DO

The Organic Acids Test (OAT) contains multiple markers which may be influenced by environmental and mold toxins. Often the combination of the OAT, MycoTOX Profile (mold toxins), and GPL-TOX Profile (environmental chemical toxins) can be used to help identify exposure sources and biochemical imbalances in individuals with chronic health conditions. This presentation by Kurt N. Woeller, DO will help connect some of the more common findings seen in practice when evaluating these three tests.

Autism, Special Needs (e.g., ADD, ADHD, pervasive development disorder) and Fungal Toxins

Kurt Woeller, DO

Autism and other special needs individuals often have biochemical and nutritional imbalances that contribute to language, socialization, and behavioral problems. In some situations, these issues are exacerbated by fungal toxins linked to chronic candidiasis and mold-produced compounds. For example, chemical aldehydes from fungus are known to be highly reactive compounds that need to be converted to less toxic forms via converting enzymes and phase detoxification within the liver. These aldehydes and other compounds can have detrimental effects within the body. The use of various nutrients such as N-acetylcysteine (NAC), etc. are often essential in supporting the body against fungal toxins. This lecture designed for health professionals, as well as parents and caregivers will discuss new information related to certain fungal toxins and strategies for treatment.

GPL-TOX: Common Markers And Environmental Testing

Jasmyne Brown, ND

This webinar will discuss some common toxins assessed on the GPL-TOX Profile. We will discuss the effects of exposure and where to find these common toxins. Briefly, we will take a look into options for testing the environment to identify potential exposure in your everyday life.

The Four Pillars of Autism Biomedical Intervention

Dr. Kurt N. Woeller has implemented his four-pillar approach to autism biomedical intervention for over two decades. This lecture will explore these four fundamental steps and why they should not be overlooked when treating individuals on the autism-spectrum.

Essential Integrative Medicine Lab Tests That Should Be Done for Anyone with Autism